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Cwp19 Is a Novel Lytic Transglycosylase Involved in Stationary-Phase Autolysis Resulting in Toxin Release in Clostridium difficile
Clostridium difficile is the major etiologic agent of antibiotic-associated intestinal disease. Pathogenesis of C. difficile is mainly attributed to the production and secretion of toxins A and B. Unlike most clostridial toxins, toxins A and B have no signal peptide, and they are therefore secreted...
Autores principales: | Wydau-Dematteis, Sandra, El Meouche, Imane, Courtin, Pascal, Hamiot, Audrey, Lai-Kuen, René, Saubaméa, Bruno, Fenaille, François, Butel, Marie-José, Pons, Jean-Louis, Dupuy, Bruno, Chapot-Chartier, Marie-Pierre, Peltier, Johann |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016235/ https://www.ncbi.nlm.nih.gov/pubmed/29895635 http://dx.doi.org/10.1128/mBio.00648-18 |
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