Four Molybdenum-Dependent Steroid C-25 Hydroxylases: Heterologous Overproduction, Role in Steroid Degradation, and Application for 25-Hydroxyvitamin D(3) Synthesis

Side chain-containing steroids are ubiquitous constituents of biological membranes that are persistent to biodegradation. Aerobic, steroid-degrading bacteria employ oxygenases for isoprenoid side chain and tetracyclic steran ring cleavage. In contrast, a Mo-containing steroid C-25 dehydrogenase (S25...

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Detalles Bibliográficos
Autores principales: Jacoby, Christian, Eipper, Jens, Warnke, Markus, Tiedt, Oliver, Mergelsberg, Mario, Stärk, Hans-Joachim, Daus, Birgit, Martín-Moldes, Zaira, Zamarro, María Teresa, Díaz, Eduardo, Boll, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016249/
https://www.ncbi.nlm.nih.gov/pubmed/29921665
http://dx.doi.org/10.1128/mBio.00694-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016249/
https://www.ncbi.nlm.nih.gov/pubmed/29921665
http://dx.doi.org/10.1128/mBio.00694-18

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