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The PGRS Domain of Mycobacterium tuberculosis PE_PGRS Protein Rv0297 Is Involved in Endoplasmic Reticulum Stress-Mediated Apoptosis through Toll-Like Receptor 4

The genome of Mycobacterium tuberculosis, the causal organism of tuberculosis (TB), encodes a unique protein family known as the PE/PPE/PGRS family, present exclusively in the genus Mycobacterium and nowhere else in the living kingdom, with largely unexplored functions. We describe the functional si...

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Detalles Bibliográficos
Autores principales: Grover, Sonam, Sharma, Tarina, Singh, Yadvir, Kohli, Sakshi, P., Manjunath, Singh, Aditi, Semmler, Torsten, Wieler, Lothar H., Tedin, Karsten, Ehtesham, Nasreen Z., Hasnain, Seyed E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016250/
https://www.ncbi.nlm.nih.gov/pubmed/29921671
http://dx.doi.org/10.1128/mBio.01017-18