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Kidney-targeted drug delivery via rhein-loaded polyethyleneglycol-co-polycaprolactone-co-polyethylenimine nanoparticles for diabetic nephropathy therapy

INTRODUCTION: Diabetic nephropathy (DN) is the primary root of morbidity and mortality in diabetic patients. Unfortunately, currently, no effective therapeutic strategies are available to ameliorate and reverse the progression of DN. Rhein (RH) is an anthraquinone derivative extracted from herbal me...

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Detalles Bibliográficos
Autores principales: Chen, Danfei, Han, Shunping, Zhu, Yongqin, Hu, Fang, Wei, Yinghui, Wang, Guowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016261/
https://www.ncbi.nlm.nih.gov/pubmed/29950832
http://dx.doi.org/10.2147/IJN.S166445