Isosteric substitution in cationic-amphiphilic polymers reveals an important role for hydrogen bonding in bacterial membrane interactions

Biomimetic antibacterial polymers, the functional mimics of antimicrobial peptides (AMPs), targeting the bacterial cell membrane have been developed to combat the problem of antibiotic resistance. Amphiphilicity, a balance of cationic charge and hydrophobicity, in these polymers has been shown to be...

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Detalles Bibliográficos
Autores principales: Uppu, D. S. S. M., Konai, M. M., Baul, U., Singh, P., Siersma, T. K., Samaddar, S., Vemparala, S., Hamoen, L. W., Narayana, C., Haldar, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016443/
https://www.ncbi.nlm.nih.gov/pubmed/30155109
http://dx.doi.org/10.1039/c6sc00615a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016443/
https://www.ncbi.nlm.nih.gov/pubmed/30155109
http://dx.doi.org/10.1039/c6sc00615a

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