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Isosteric substitution in cationic-amphiphilic polymers reveals an important role for hydrogen bonding in bacterial membrane interactions
Biomimetic antibacterial polymers, the functional mimics of antimicrobial peptides (AMPs), targeting the bacterial cell membrane have been developed to combat the problem of antibiotic resistance. Amphiphilicity, a balance of cationic charge and hydrophobicity, in these polymers has been shown to be...
Autores principales: | Uppu, D. S. S. M., Konai, M. M., Baul, U., Singh, P., Siersma, T. K., Samaddar, S., Vemparala, S., Hamoen, L. W., Narayana, C., Haldar, J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016443/ https://www.ncbi.nlm.nih.gov/pubmed/30155109 http://dx.doi.org/10.1039/c6sc00615a |
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