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Structural determinants in a glucose-containing lipopolysaccharide from Mycobacterium tuberculosis critical for inducing a subset of protective T cells

Mycobacteria synthesize intracellular, 6-O-methylglucose–containing lipopolysaccharides (mGLPs) proposed to modulate bacterial fatty acid metabolism. Recently, it has been shown that Mycobacterium tuberculosis mGLP specifically induces a specific subset of protective γ(9)δ(2) T cells. Mild base trea...

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Detalles Bibliográficos
Autores principales: De, Prithwiraj, McNeil, Michael, Xia, Mei, Boot, Claudia M., Hesser, Danny C., Denef, Karolien, Rithner, Christopher, Sours, Tyler, Dobos, Karen M., Hoft, Daniel, Chatterjee, Delphi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016469/
https://www.ncbi.nlm.nih.gov/pubmed/29716995
http://dx.doi.org/10.1074/jbc.RA118.002582