Control of mitochondrial superoxide production by reverse electron transport at complex I

The generation of mitochondrial superoxide (O(2)(˙̄)) by reverse electron transport (RET) at complex I causes oxidative damage in pathologies such as ischemia reperfusion injury, but also provides the precursor to H(2)O(2) production in physiological mitochondrial redox signaling. Here, we quantifie...

Descripción completa

Detalles Bibliográficos
Autores principales: Robb, Ellen L., Hall, Andrew R., Prime, Tracy A., Eaton, Simon, Szibor, Marten, Viscomi, Carlo, James, Andrew M., Murphy, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Bioenergetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016480/
https://www.ncbi.nlm.nih.gov/pubmed/29743240
http://dx.doi.org/10.1074/jbc.RA118.003647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016480/
https://www.ncbi.nlm.nih.gov/pubmed/29743240
http://dx.doi.org/10.1074/jbc.RA118.003647

Ejemplares similares