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ARL11 regulates lipopolysaccharide-stimulated macrophage activation by promoting mitogen-activated protein kinase (MAPK) signaling

ADP-ribosylation factor-like GTPase 11 (ARL11) is a cancer-predisposing gene that has remained functionally uncharacterized to date. In this study, we report that ARL11 is endogenously expressed in mouse and human macrophages and regulates their activation in response to lipopolysaccharide (LPS) sti...

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Detalles Bibliográficos
Autores principales: Arya, Subhash B., Kumar, Gaurav, Kaur, Harmeet, Kaur, Amandeep, Tuli, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016484/
https://www.ncbi.nlm.nih.gov/pubmed/29618517
http://dx.doi.org/10.1074/jbc.RA117.000727