Targeting the dopamine D(1) receptor or its downstream signalling by inhibiting phosphodiesterase‐1 improves cognitive performance

BACKGROUND AND PURPOSE: Insufficient prefrontal dopamine 1 (D(1)) receptor signalling has been linked to cognitive dysfunction in several psychiatric conditions. Because the PDE1 isoform B (PDE1B) is postulated to regulate D(1) receptor‐dependent signal transduction, in this study we aimed to elucid...

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Detalles Bibliográficos
Autores principales: Pekcec, Anton, Schülert, Niklas, Stierstorfer, Birgit, Deiana, Serena, Dorner‐Ciossek, Cornelia, Rosenbrock, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016630/
https://www.ncbi.nlm.nih.gov/pubmed/29726015
http://dx.doi.org/10.1111/bph.14350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016630/
https://www.ncbi.nlm.nih.gov/pubmed/29726015
http://dx.doi.org/10.1111/bph.14350

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