A stress-induced response complex (SIRC) shuttles miRNAs, siRNAs, and oligonucleotides to the nucleus

Although some information is available for specific subsets of miRNAs and several factors have been shown to bind oligonucleotides (ONs), no general transport mechanism for these molecules has been identified to date. In this work, we demonstrate that the nuclear transport of ONs, siRNAs, and miRNAs...

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Detalles Bibliográficos
Autores principales: Castanotto, Daniela, Zhang, Xiaowei, Alluin, Jessica, Zhang, Xizhe, Rüger, Jacqueline, Armstrong, Brian, Rossi, John, Riggs, Arthur, Stein, C. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016802/
https://www.ncbi.nlm.nih.gov/pubmed/29866826
http://dx.doi.org/10.1073/pnas.1721346115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016802/
https://www.ncbi.nlm.nih.gov/pubmed/29866826
http://dx.doi.org/10.1073/pnas.1721346115

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