Cargando…

Metformin suppresses UHMWPE particle-induced osteolysis in the mouse calvaria by promoting polarization of macrophages to an anti-inflammatory phenotype

BACKGROUND: Implant failure remains a major obstacle to successful treatment via TJA. Periprosthetic osteolysis and aseptic loosening are considered as proof of wear debris-induced disruption of local regulatory mechanisms related to excessive bone resorption associated with osteolysis and the damag...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yan, Zhao, Tian, Xiaoxi, Zhu, Jinyu, Lu, Zifan, Yu, Lifeng, Zhang, Dawei, Liu, Yanwu, Yang, Chongfei, Zhu, Qingsheng, Cao, Xiaorui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016863/ https://www.ncbi.nlm.nih.gov/pubmed/30134793 http://dx.doi.org/10.1186/s10020-018-0013-x

Ejemplares similares

Pyrroloquinoline Quinine Inhibits RANKL-Mediated Expression of NFATc1 in Part via Suppression of c-Fos in Mouse Bone Marrow Cells and Inhibits Wear Particle-Induced Osteolysis in Mice
por: Kong, Lingbo, et al.
Publicado: (2013)

Niobium carbide (MXene) reduces UHMWPE particle-induced osteolysis
por: Sun, Kuo-Yang, et al.
Publicado: (2021)

Increased UHMWPE Particle-Induced Osteolysis in Fetuin-A-Deficient Mice
por: Polan, Christina, et al.
Publicado: (2023)

Surgical Modification of the Murine Calvaria Osteolysis Model
por: Al-quhali, Ali Mohammed, et al.
Publicado: (2015)

Macrophage inhibits the osteogenesis of fibroblasts in ultrahigh molecular weight polyethylene (UHMWPE) wear particle-induced osteolysis
por: Lei, Pengfei, et al.
Publicado: (2019)

Impact of vitamin E-blended UHMWPE wear particles on the osseous microenvironment in polyethylene particle-induced osteolysis
por: Neuerburg, Carl, et al.
Publicado: (2016)

In Vivo Imaging of Particle-Induced Inflammation and Osteolysis in the Calvariae of NFκB/Luciferase Transgenic Mice
por: Takahashi, Kunihiko, et al.
Publicado: (2011)

Desferrioxamine alleviates UHMWPE particle-induced osteoclastic osteolysis by inhibiting caspase-1-dependent pyroptosis in osteocytes
por: Zhao, Shenli, et al.
Publicado: (2022)

Treatment Effects of the Second-Generation Tyrosine Kinase Inhibitor Dasatinib on Autoimmune Arthritis
por: Guo, Kai, et al.
Publicado: (2019)

A review of UHMWPE wear-induced osteolysis: the role for early detection of the immune response
por: Kandahari, Adrese M, et al.
Publicado: (2016)

Pyrroloquinoline Quinone (PQQ) Inhibits Lipopolysaccharide Induced Inflammation in Part via Downregulated NF-κB and p38/JNK Activation in Microglial and Attenuates Microglia Activation in Lipopolysaccharide Treatment Mice
por: Yang, Chongfei, et al.
Publicado: (2014)

Osthole Inhibits M1 Macrophage Polarization and Attenuates Osteolysis in a Mouse Skull Model
por: Wang, Feifei, et al.
Publicado: (2023)

Anti-oxidation Treatment of Ultra High Molecular Weight Polyethylene Components to Decrease Periprosthetic Osteolysis: Evaluation of Osteolytic and Osteogenic Properties of Wear Debris Particles in a Murine Calvaria Model
por: Green, Justin M., et al.
Publicado: (2013)

Mechanism of regulating macrophages/osteoclasts in attenuating wear particle-induced aseptic osteolysis
por: Yin, Zhaoyang, et al.
Publicado: (2023)

Macrophage Response to UHMWPE Submitted to Accelerated Ageing in Hydrogen Peroxide
por: Rocha, Magda F.G., et al.
Publicado: (2010)

Recent Advances in UHMWPE/UHMWPE Nanocomposite/UHMWPE Hybrid Nanocomposite Polymer Coatings for Tribological Applications: A Comprehensive Review
por: Abdul Samad, Mohammed
Publicado: (2021)

Study of UHMWPE Fiber Surface Modification and the Properties of UHMWPE/Epoxy Composite
por: Han, Lei, et al.
Publicado: (2020)

Prednisone prevents particle induced bone loss in the calvaria mouse model
por: Schündeln, Michael M., et al.
Publicado: (2021)

Anti-Ballistic Performance of PPTA/UHMWPE Laminates
por: Zhu, Long, et al.
Publicado: (2023)

CoCrMo alloy vs. UHMWPE Particulate Implant Debris Induces Sex Dependent Aseptic Osteolysis Responses In Vivo using a Murine Model
por: Landgraeber, Stefan, et al.
Publicado: (2018)

Identification of Key Candidate Genes Related to Inflammatory Osteolysis Associated with Vitamin E-Blended UHMWPE Debris of Orthopedic Implants by Integrated Bioinformatics Analysis and Experimental Confirmation
por: Liu, Fanxiao, et al.
Publicado: (2021)

Metformin Regulates Alveolar Macrophage Polarization to Protect Against Acute Lung Injury in Rats Caused by Paraquat Poisoning
por: Yuan, Ding, et al.
Publicado: (2022)

Oestrogen deficiency modulates particle-induced osteolysis
por: Nich, Christophe, et al.
Publicado: (2011)

IRAK-4 in macrophages contributes to inflammatory osteolysis of wear particles around loosened hip implants
por: Zhang, Yang-chun, et al.
Publicado: (2021)

UHMWPE for arthroplasty: past or future?
por: Brach del Prever, Elena Maria, et al.
Publicado: (2008)

Puerarin Exerts Protective Effects on Wear Particle-Induced Inflammatory Osteolysis
por: Yang, Chao, et al.
Publicado: (2019)

Mechanism and Prevention of Titanium Particle-Induced Inflammation and Osteolysis
por: Eger, Michal, et al.
Publicado: (2018)

A Child without Calvaria or Brain
por: Redmond, L.
Publicado: (1869)

BMP-2 functional polypeptides relieve osteolysis via bi-regulating bone formation and resorption coupled with macrophage polarization
por: Wang, Jiaqian, et al.
Publicado: (2023)

Wear and Friction of UHMWPE-on-PEEK OPTIMA™
por: Cowie, Raelene M., et al.
Publicado: (2019)

Photoluminescent carbon dots (PCDs) from sour apple: a biocompatible nanomaterial for preventing UHMWPE wear-particle induced osteolysis via modulating Chemerin/ChemR23 and SIRT1 signaling pathway and its bioimaging application
por: Li, Xiang, et al.
Publicado: (2022)

Protection Effect of Curcumin for Macrophage-Involved Polyethylene Wear Particle-Induced Inflammatory Osteolysis by Increasing the Cholesterol Efflux
por: Liu, Yu-wei, et al.
Publicado: (2019)

Calcitonin substitution in calcitonin deficiency reduces particle-induced osteolysis
por: Kauther, Max D, et al.
Publicado: (2011)

Britanin inhibits titanium wear particle‑induced osteolysis and osteoclastogenesis
por: Kim, Ju Ang, et al.
Publicado: (2023)

Design and Characterization of the Surface Porous UHMWPE Composite Reinforced by Graphene Oxide
por: Chen, Xiaohong, et al.
Publicado: (2021)

Nanomechanical and surface properties of rMSCs post-exposure to CAP treated UHMWPE wear particles
por: Preedy, Emily Callard, et al.
Publicado: (2016)

Alendronate Release from UHMWPE-Based Biomaterials in Relation to Particle Size of the GUR Powder for Manufacturing
por: Seidenstuecker, Michael, et al.
Publicado: (2019)

Acro-osteolysis
por: Thomas, Joe, et al.
Publicado: (2019)

Decellularized bone matrix grafts for calvaria regeneration
por: Lee, Dong Joon, et al.
Publicado: (2016)

Third Body Wear of UHMWPE-on-PEEK-OPTIMA™
por: Cowie, Raelene M., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_p374h30gl00ui0u7ajgb0hhcvn