Advances in therapeutic use of a drug-stimulated translational readthrough of premature termination codons

Premature termination codons (PTCs) in the coding regions of mRNA lead to the incorrect termination of translation and generation of non-functional, truncated proteins. Translational readthrough of PTCs induced by pharmaceutical compounds is a promising way of restoring functional protein expression...

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Detalles Bibliográficos
Autores principales: Dabrowski, Maciej, Bukowy-Bieryllo, Zuzanna, Zietkiewicz, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016875/
https://www.ncbi.nlm.nih.gov/pubmed/30134808
http://dx.doi.org/10.1186/s10020-018-0024-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016875/
https://www.ncbi.nlm.nih.gov/pubmed/30134808
http://dx.doi.org/10.1186/s10020-018-0024-7

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