Cargando…

Effects of CREB1 gene silencing on cognitive dysfunction by mediating PKA-CREB signaling pathway in mice with vascular dementia

BACKGROUND: As a form of dementia primarily affecting the elderly, vascular dementia (VD) is characterized by changes in the supply of blood to the brain, resulting in cognitive impairment. The aim of the present study was to explore the effects involved with cyclic adenosine monophosphate (cAMP) re...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Xin-Rui, Wen, Xin, Wang, Yong-Jian, Wang, Shan, Shen, Min, Zhang, Zi-Feng, Fan, Shao-Hua, Shan, Qun, Wang, Liang, Li, Meng-Qiu, Hu, Bin, Sun, Chun-Hui, Wu, Dong-Mei, Lu, Jun, Zheng, Yuan-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016877/
https://www.ncbi.nlm.nih.gov/pubmed/30134805
http://dx.doi.org/10.1186/s10020-018-0020-y