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Uncoupling of glycolysis from glucose oxidation accompanies the development of heart failure with preserved ejection fraction
BACKGROUND: Alterations in cardiac energy metabolism contribute to the development and severity of heart failure (HF). In severe HF, overall mitochondrial oxidative metabolism is significantly decreased resulting in a reduced energy reserve. However, despite the high prevalence of HF with preserved...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016884/ https://www.ncbi.nlm.nih.gov/pubmed/30134787 http://dx.doi.org/10.1186/s10020-018-0005-x |