Uncoupling of glycolysis from glucose oxidation accompanies the development of heart failure with preserved ejection fraction

BACKGROUND: Alterations in cardiac energy metabolism contribute to the development and severity of heart failure (HF). In severe HF, overall mitochondrial oxidative metabolism is significantly decreased resulting in a reduced energy reserve. However, despite the high prevalence of HF with preserved...

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Detalles Bibliográficos
Autores principales: Fillmore, Natasha, Levasseur, Jody L., Fukushima, Arata, Wagg, Cory S., Wang, Wei, Dyck, Jason R. B., Lopaschuk, Gary D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016884/
https://www.ncbi.nlm.nih.gov/pubmed/30134787
http://dx.doi.org/10.1186/s10020-018-0005-x

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