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MicroRNA and Transcriptomic Profiling Showed miRNA-Dependent Impairment of Systemic Regulation and Synthesis of Biomolecules in Rag2 KO Mice

The Rag2 knockout (KO) mouse is a well-established immune-compromised animal model for biomedical research. A comparative study identified the deregulated expression of microRNAs (miRNAs) and messenger RNAs (mRNAs) in Rag2 KO mice. However, the interaction between deregulated genes and miRNAs in the...

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Detalles Bibliográficos
Autores principales: Reza, Abu Musa Md Talimur, Choi, Yun-Jung, Kim, Jin-Hoi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017002/
https://www.ncbi.nlm.nih.gov/pubmed/29495457
http://dx.doi.org/10.3390/molecules23030527