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[(18)F]fallypride-PET/CT Analysis of the Dopamine D(2)/D(3) Receptor in the Hemiparkinsonian Rat Brain Following Intrastriatal Botulinum Neurotoxin A Injection

Intrastriatal injection of botulinum neurotoxin A (BoNT-A) results in improved motor behavior of hemiparkinsonian (hemi-PD) rats, an animal model for Parkinson’s disease. The caudate–putamen (CPu), as the main input nucleus of the basal ganglia loop, is fundamentally involved in motor function and d...

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Detalles Bibliográficos
Autores principales: Mann, Teresa, Kurth, Jens, Hawlitschka, Alexander, Stenzel, Jan, Lindner, Tobias, Polei, Stefan, Hohn, Alexander, Krause, Bernd J., Wree, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017015/
https://www.ncbi.nlm.nih.gov/pubmed/29509680
http://dx.doi.org/10.3390/molecules23030587