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N-Salicyloyltryptamine, an N-Benzoyltryptamine Analogue, Induces Vasorelaxation through Activation of the NO/sGC Pathway and Reduction of Calcium Influx

Benzoyltryptamine analogues act as neuroprotective and spasmolytic agents on smooth muscles. In this study, we investigated the ability of N-salicyloyltryptamine (STP) to produce vasorelaxation and determined its underlying mechanisms of action. Isolated rat mesenteric arteries with and without func...

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Detalles Bibliográficos
Autores principales: Veras, Robson Cavalcante, Silva, Darizy Flávia, Bezerra, Lorena Soares, de Assis, Valéria Lopes, de Vasconcelos, Walma Pereira, Alustau, Maria do Carmo, de Albuquerque, José George Ferreira, Furtado, Fabíola Fialho, Araújo, Islania Giselia de Albuquerque, de Azevedo, Fátima de Lourdes Assunção Araújo, Ribeiro, Thais Porto, Barbosa-Filho, José Maria, Gutierrez, Stanley Juan Chavez, Medeiros, Isac Almeida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017111/
https://www.ncbi.nlm.nih.gov/pubmed/29382081
http://dx.doi.org/10.3390/molecules23020253