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Melatonin Balance the Autophagy and Apoptosis by Regulating UCP2 in the LPS-Induced Cardiomyopathy

To explore the mechanism of mitochondrial uncoupling protein 2 (UCP2) mediating the protective of melatonin when septic cardiomyopathy. UCP2 knocked out mice and cardiomyocytes were used to study the effect of melatonin in response to LPS. Indicators of myocardial and mitochondria injury including m...

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Detalles Bibliográficos
Autores principales: Pan, Pan, Zhang, Hongmin, Su, Longxiang, Wang, Xiaoting, Liu, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017117/
https://www.ncbi.nlm.nih.gov/pubmed/29547569
http://dx.doi.org/10.3390/molecules23030675