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Melatonin Balance the Autophagy and Apoptosis by Regulating UCP2 in the LPS-Induced Cardiomyopathy
To explore the mechanism of mitochondrial uncoupling protein 2 (UCP2) mediating the protective of melatonin when septic cardiomyopathy. UCP2 knocked out mice and cardiomyocytes were used to study the effect of melatonin in response to LPS. Indicators of myocardial and mitochondria injury including m...
Autores principales: | Pan, Pan, Zhang, Hongmin, Su, Longxiang, Wang, Xiaoting, Liu, Dawei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017117/ https://www.ncbi.nlm.nih.gov/pubmed/29547569 http://dx.doi.org/10.3390/molecules23030675 |
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