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Structural Insights into σ(1) Receptor Interactions with Opioid Ligands by Molecular Dynamics Simulations

Despite considerable advances over the past years in understanding the mechanisms of action and the role of the σ(1) receptor, several questions regarding this receptor remain unanswered. This receptor has been identified as a useful target for the treatment of a diverse range of diseases, from vari...

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Detalles Bibliográficos
Autores principales: Kurciński, Mateusz, Jarończyk, Małgorzata, Lipiński, Piotr F. J., Dobrowolski, Jan Cz., Sadlej, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017133/
https://www.ncbi.nlm.nih.gov/pubmed/29463040
http://dx.doi.org/10.3390/molecules23020456