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Syntheses of 1-Aryl-5-nitro-1H-indazoles and a General One-Pot Route to 1-Aryl-1H-indazoles

An efficient route to substituted 1-aryl-1H-indazoles has been developed and optimized. The method involved the preparation of arylhydrazones from acetophenone or benzaldehyde substituted by fluorine at C2 and nitro at C5, followed by deprotonation and nucleophilic aromatic substitution (S(N)Ar) rin...

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Detalles Bibliográficos
Autores principales: Annor-Gyamfi, Joel K., Gnanasekaran, Krishna Kumar, Bunce, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017161/
https://www.ncbi.nlm.nih.gov/pubmed/29547568
http://dx.doi.org/10.3390/molecules23030674