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Synthesis and Evaluation of Bakuchiol Derivatives as Potential Anticancer Agents

A series of bakuchiol derivatives were synthesized and evaluated for their anti-proliferative and the inhibitory activities on SMMC7721 cell line migration using PX-478 as a positive control. The results showed (S,E)-4-(7-methoxy-3,7-dimethyl-3-vinyloct-1-en-1-yl)phenol (10) to have the best activit...

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Detalles Bibliográficos
Autores principales: Wu, Cheng-Zhu, Liu, Da-Chuan, Guo, Xing, Dai, Yiqun, Ma, Tao, Li, Hong-Mei, Huo, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017251/
https://www.ncbi.nlm.nih.gov/pubmed/29495380
http://dx.doi.org/10.3390/molecules23030515