Exploration of the Inhibitory Potential of Varespladib for Snakebite Envenomation

Phospholipase A(2)s (PLA(2)) is a major component of snake venom with diverse pathologic toxicities and, therefore, a potential target for antivenom therapy. Varespladib was initially designed as an inhibitor of mammal PLA(2)s, and was recently repurposed to a broad-spectrum inhibitor of PLA(2) in s...

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Detalles Bibliográficos
Autores principales: Wang, Yiding, Zhang, Jing, Zhang, Denghong, Xiao, Huixiang, Xiong, Shengwei, Huang, Chunhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017252/
https://www.ncbi.nlm.nih.gov/pubmed/29439513
http://dx.doi.org/10.3390/molecules23020391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017252/
https://www.ncbi.nlm.nih.gov/pubmed/29439513
http://dx.doi.org/10.3390/molecules23020391

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