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Exploration of the Inhibitory Potential of Varespladib for Snakebite Envenomation
Phospholipase A(2)s (PLA(2)) is a major component of snake venom with diverse pathologic toxicities and, therefore, a potential target for antivenom therapy. Varespladib was initially designed as an inhibitor of mammal PLA(2)s, and was recently repurposed to a broad-spectrum inhibitor of PLA(2) in s...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017252/ https://www.ncbi.nlm.nih.gov/pubmed/29439513 http://dx.doi.org/10.3390/molecules23020391 |