Towards a Novel Class of Multitarget-Directed Ligands: Dual P2X7–NMDA Receptor Antagonists

Multi-target-directed ligands (MTDLs) offer new hope for the treatment of multifactorial complex diseases such as Alzheimer’s Disease (AD). Herein, we present compounds aimed at targeting the NMDA and the P2X7 receptors, which embody a different approach to AD therapy. On one hand, we are seeking to...

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Detalles Bibliográficos
Autores principales: Karoutzou, Olga, Kwak, Seung-Hwa, Lee, So-Deok, Martínez-Falguera, Daina, Sureda, Francesc X., Vázquez, Santiago, Kim, Yong-Chul, Barniol-Xicota, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017257/
https://www.ncbi.nlm.nih.gov/pubmed/29361735
http://dx.doi.org/10.3390/molecules23010230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017257/
https://www.ncbi.nlm.nih.gov/pubmed/29361735
http://dx.doi.org/10.3390/molecules23010230

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