Advances in the Development of PET Ligands Targeting Histone Deacetylases for the Assessment of Neurodegenerative Diseases

Epigenetic alterations of gene expression have emerged as a key factor in several neurodegenerative diseases. In particular, inhibitors targeting histone deacetylases (HDACs), which are enzymes responsible for deacetylation of histones and other proteins, show therapeutic effects in animal neurodege...

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Detalles Bibliográficos
Autores principales: Tago, Tetsuro, Toyohara, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017260/
https://www.ncbi.nlm.nih.gov/pubmed/29385079
http://dx.doi.org/10.3390/molecules23020300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017260/
https://www.ncbi.nlm.nih.gov/pubmed/29385079
http://dx.doi.org/10.3390/molecules23020300

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