Cargando…

A Sample and Sensitive HPLC-MS/MS Method for Simultaneous Determination of Ziyuglycoside I and Its Metabolite Ziyuglycoside II in Rat Pharmacokinetics

Ziyuglycoside I (ZGS1) is a promising drug candidate for the treatment of leucopenia. Currently, information on ZGS1 and its in vivo metabolite ziyuglycoside II (ZGS2) is limited. The objective of this study was to investigate the pharmacokinetics, tissue distribution, and excretion of ziyuglycoside...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Zhi-Feng, Zhou, Meng-Ying, Tan, Ting, Zhong, Chen-Cong, Wang, Qi, Pan, Ling-Ling, Luo, Ying-Ying, Yang, Shi-Lin, Feng, Yu-Lin, Ouyang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017276/
https://www.ncbi.nlm.nih.gov/pubmed/29495641
http://dx.doi.org/10.3390/molecules23030543