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Synthesis and Evaluation of the Anticonvulsant Activities of 4-(2-(Alkylthio)benzo[d]oxazol-5-yl)-2,4-dihydro-3H-1,2,4-triazol-3-ones

In this study, a novel series of 4-(2-(alkylthio)benzo[d]oxazol-5-yl)-2,4-dihydro-3H-1,2,4-triazol-3-ones (4a–m) was designed and synthesized. The anticonvulsant activities of these compounds were evaluated by using the maximal electroshock seizure (MES) and subcutaneous pentylenetetrazole (scPTZ) s...

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Detalles Bibliográficos
Autores principales: Song, Ming-Xia, Wang, Zhen-Yuan, He, Shi-Hui, Yu, Sheng-Wang, Chen, Shi-Long, Guo, Dong-Fu, Zhao, Wen-Hao, Deng, Xian-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017283/
https://www.ncbi.nlm.nih.gov/pubmed/29587394
http://dx.doi.org/10.3390/molecules23040756