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Oleanolic Acid-amino Acids Derivatives: Design, Synthesis, and Hepatoprotective Evaluation In Vitro and In Vivo

Activated hepatic stellate cells (HSCs) are the main extracellular matrix (ECM)-producing cells in the injured liver and the key mediators of liver fibrosis; they also promote the progression of hepatocellular carcinoma (HCC). In the acidic extracellular microenvironment of HCC, HSCs are activated t...

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Detalles Bibliográficos
Autores principales: Chu, Fuhao, Zhang, Wenxi, Guo, Wenbo, Wang, Zhaoyi, Yang, Yuqin, Zhang, Xinyu, Fang, Kang, Yan, Mengmeng, Wang, Penglong, Lei, Haimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017290/
https://www.ncbi.nlm.nih.gov/pubmed/29393898
http://dx.doi.org/10.3390/molecules23020322