Potent GH20 N-Acetyl-β-d-hexosaminidase Inhibitors: N-Substituted 3-acetamido-4-amino-5-hydroxymethyl-cyclopentanediols

From 1,2;3,4-di-O-isopropylidene-d-galactopyranose, a preliminary series of highly functionalized amino(hydroxymethyl)cyclopentanes was easily available. These amine-containing basic carbasugars featuring the d-galacto configuration are potent inhibitors of the GH20 β-d-hexosaminidases probed and ma...

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Detalles Bibliográficos
Autores principales: Weber, Patrick, Nasseri, Seyed A., Pabst, Bettina M., Torvisco, Ana, Müller, Philipp, Paschke, Eduard, Tschernutter, Marion, Windischhofer, Werner, Withers, Stephen G., Wrodnigg, Tanja M., Stütz, Arnold E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017319/
https://www.ncbi.nlm.nih.gov/pubmed/29558439
http://dx.doi.org/10.3390/molecules23030708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017319/
https://www.ncbi.nlm.nih.gov/pubmed/29558439
http://dx.doi.org/10.3390/molecules23030708

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