Cell Penetrating Capacity and Internalization Mechanisms Used by the Synthetic Peptide CIGB-552 and Its Relationship with Tumor Cell Line Sensitivity

CIGB-552 is a twenty-amino-acid novel synthetic peptide that has proven to be effective in reducing tumor size and increasing lifespan in tumor-bearing mice. Such capability is conferred by its cell-penetrating peptide character, which allows it to enter cells and elicit a pro-apoptotic effect throu...

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Detalles Bibliográficos
Autores principales: Astrada, Soledad, Fernández Massó, Julio Raúl, Vallespí, Maribel G., Bollati-Fogolín, Mariela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017325/
https://www.ncbi.nlm.nih.gov/pubmed/29601540
http://dx.doi.org/10.3390/molecules23040801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017325/
https://www.ncbi.nlm.nih.gov/pubmed/29601540
http://dx.doi.org/10.3390/molecules23040801

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