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Bacterial Production, Characterization and Protein Modeling of a Novel Monofuctional Isoform of FAD Synthase in Humans: An Emergency Protein?

FAD synthase (FADS, EC 2.7.7.2) is the last essential enzyme involved in the pathway of biosynthesis of Flavin cofactors starting from Riboflavin (Rf). Alternative splicing of the human FLAD1 gene generates different isoforms of the enzyme FAD synthase. Besides the well characterized isoform 1 and 2...

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Detalles Bibliográficos
Autores principales: Leone, Piero, Galluccio, Michele, Barbiroli, Alberto, Eberini, Ivano, Tolomeo, Maria, Vrenna, Flavia, Gianazza, Elisabetta, Iametti, Stefania, Bonomi, Francesco, Indiveri, Cesare, Barile, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017331/
https://www.ncbi.nlm.nih.gov/pubmed/29316637
http://dx.doi.org/10.3390/molecules23010116