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The Effects of Aronia melanocarpa ‘Viking’ Extracts in Attenuating RANKL-Induced Osteoclastic Differentiation by Inhibiting ROS Generation and c-FOS/NFATc1 Signaling

This study aimed to determine the anti-osteoclastogenic effects of extracts from Aronia melanocarpa ‘Viking’ (AM) and identify the underlying mechanisms in vitro. Reactive oxygen species (ROS) are signal mediators in osteoclast differentiation. AM extracts inhibited ROS production in RAW 264.7 cells...

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Detalles Bibliográficos
Autores principales: Ghosh, Mithun, Kim, In Sook, Lee, Young Min, Hong, Seong Min, Lee, Taek Hwan, Lim, Ji Hong, Debnath, Trishna, Lim, Beong Ou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017336/
https://www.ncbi.nlm.nih.gov/pubmed/29518052
http://dx.doi.org/10.3390/molecules23030615