Discovery of Oxime Ethers as Hepatitis B Virus (HBV) Inhibitors by Docking, Screening and In Vitro Investigation

A series of oxime ethers with C(6)-C(4) fragment was designed and virtually bioactively screened by docking with a target, then provided by a Friedel–Crafts reaction, esterification (or amidation), and oximation from p-substituted phenyl derivatives (Methylbenzene, Methoxybenzene, Chlorobenzene). An...

Descripción completa

Detalles Bibliográficos
Autores principales: Tan, Jie, Zhou, Min, Cui, Xinhua, Wei, Zhuocai, Wei, Wanxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017342/
https://www.ncbi.nlm.nih.gov/pubmed/29534537
http://dx.doi.org/10.3390/molecules23030637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017342/
https://www.ncbi.nlm.nih.gov/pubmed/29534537
http://dx.doi.org/10.3390/molecules23030637

Ejemplares similares