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In Silico-Based Repositioning of Phosphinothricin as a Novel Technetium-99m Imaging Probe with Potential Anti-Cancer Activity

l-Phosphinothricin (glufosinate or 2-amino-4-((hydroxy(methyl) phosphinyl) butyric acid ammonium salt (AHPB)), which is a structural analog of glutamate, is a recognized herbicide that acts on weeds through inhibition of glutamine synthetase. Due to the structural similarity between phosphinothricin...

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Detalles Bibliográficos
Autores principales: Sakr, Tamer M., Khedr, Mohammed A., Rashed, Hassan M., Mohamed, Maged E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017358/
https://www.ncbi.nlm.nih.gov/pubmed/29473879
http://dx.doi.org/10.3390/molecules23020496