Synthesis and Physicochemical Evaluation of Entecavir-Fatty Acid Conjugates in Reducing Food Effect on Intestinal Absorption

The oral bioavailability of entecavir (EV), an anti-viral agent commonly prescribed to treat hepatitis B infections, is drastically reduced under a post-prandial state. This is primarily due to its low permeability in the gastrointestinal tract. To reduce the food effect on the intestinal absorption...

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Detalles Bibliográficos
Autores principales: Jung, Hyuck Jun, Ho, Myoung Jin, Ahn, Sungwan, Han, Young Taek, Kang, Myung Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017406/
https://www.ncbi.nlm.nih.gov/pubmed/29565327
http://dx.doi.org/10.3390/molecules23040731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017406/
https://www.ncbi.nlm.nih.gov/pubmed/29565327
http://dx.doi.org/10.3390/molecules23040731

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