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A Mild Aqueous Sonogashira Reaction as a Fluorescent Labeling Strategy for 5-Bromide-2′-Deoxyuridine

C5-modified uridines are a valuable class of nucleoside analogues, both as potent chemotherapy agents and through their use as the conjunction site in DNA labeling strategies. As an important C5-modified uridine, BrdU has been used in cell proliferation assays since the 1980s. Currently, the detecti...

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Detalles Bibliográficos
Autores principales: Wang, Shufang, Gao, Yongxin, Shen, Shigang, Wen, Hui, Cui, Huaqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017456/
https://www.ncbi.nlm.nih.gov/pubmed/29329267
http://dx.doi.org/10.3390/molecules23010154