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Design, Synthesis, and Biological Evaluation of 2-(Benzylamino-2-Hydroxyalkyl)Isoindoline-1,3-Diones Derivatives as Potential Disease-Modifying Multifunctional Anti-Alzheimer Agents

The complex nature of Alzheimer’s disease calls for multidirectional treatment. Consequently, the search for multi-target-directed ligands may lead to potential drug candidates. The aim of the present study is to seek multifunctional compounds with expected activity against disease-modifying and sym...

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Detalles Bibliográficos
Autores principales: Panek, Dawid, Więckowska, Anna, Pasieka, Anna, Godyń, Justyna, Jończyk, Jakub, Bajda, Marek, Knez, Damijan, Gobec, Stanislav, Malawska, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017481/
https://www.ncbi.nlm.nih.gov/pubmed/29414887
http://dx.doi.org/10.3390/molecules23020347