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Influence of Kartogenin on Chondrogenic Differentiation of Human Bone Marrow-Derived MSCs in 2D Culture and in Co-Cultivation with OA Osteochondral Explant

Articular cartilage has limited capacity for natural regeneration and repair. In the present study, we evaluated kartogenin (KGN), a bioactive small heterocyclic molecule, for its effect on in vitro proliferation and chondrogenic differentiation of human bone marrow-derived mesenchymal stromal cells...

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Detalles Bibliográficos
Autores principales: Spakova, Timea, Plsikova, Jana, Harvanova, Denisa, Lacko, Marek, Stolfa, Stefan, Rosocha, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017512/
https://www.ncbi.nlm.nih.gov/pubmed/29337871
http://dx.doi.org/10.3390/molecules23010181