Tamm–Horsfall Protein is a Potent Immunomodulatory Molecule and a Disease Biomarker in the Urinary System

Tamm–Horsfall protein (THP), or uromodulin (UMOD), is an 80–90-kDa phosphatidylinositol-anchored glycoprotein produced exclusively by the renal tubular cells in the thick ascending limb of the loop of Henle. Physiologically, THP is implicated in renal countercurrent gradient formation, sodium homeos...

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Detalles Bibliográficos
Autores principales: Wu, Tsai-Hung, Li, Ko-Jen, Yu, Chia-Li, Tsai, Chang-Youh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017547/
https://www.ncbi.nlm.nih.gov/pubmed/29361765
http://dx.doi.org/10.3390/molecules23010200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017547/
https://www.ncbi.nlm.nih.gov/pubmed/29361765
http://dx.doi.org/10.3390/molecules23010200

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