Pharmacokinetic–Pharmacodynamic Model for the Testosterone-Suppressive Effect of Leuprolide in Normal and Prostate Cancer Rats

This study developed the pharmacokinetic (PK)–pharmacodynamic (PD) model of the testosterone-suppressive effect of leuprolide for evaluation of the sustained release (SR) depot and leuprolide solution in rats with or without prostate cancer. Six groups of rats were divided by the routes of administr...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Dong-Seok, Kim, Sook-Jin, Choi, Go-Wun, Lee, Yong-Bok, Cho, Hea-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017563/
https://www.ncbi.nlm.nih.gov/pubmed/29662027
http://dx.doi.org/10.3390/molecules23040909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017563/
https://www.ncbi.nlm.nih.gov/pubmed/29662027
http://dx.doi.org/10.3390/molecules23040909

Ejemplares similares