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Synthesis of Novel C-2- or C-15-Labeled BODIPY—Estrone Conjugates

Novel BODIPY–estrone conjugates were synthesized via Cu(I)-catalyzed azide–alkyne cycloaddition (CuAAC). Estrone-alkynes or an estrone-azide as starting compounds were synthesized via Michael addition or Sonogashira reaction as key steps. Fluorescent dyes based on BODIPY-core were provided by azide...

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Detalles Bibliográficos
Autores principales: Bacsa, Ildikó, Konc, Csilla, Orosz, Anna Boglárka, Kecskeméti, Gábor, Rigó, Réka, Özvegy-Laczka, Csilla, Mernyák, Erzsébet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017578/
https://www.ncbi.nlm.nih.gov/pubmed/29614041
http://dx.doi.org/10.3390/molecules23040821