Treatment of Multidrug-Resistant Leukemia Cells by Novel Artemisinin-, Egonol-, and Thymoquinone-Derived Hybrid Compounds

Two major obstacles for successful cancer treatment are the toxicity of cytostatics and the development of drug resistance in cancer cells during chemotherapy. Acquired or intrinsic drug resistance is responsible for almost 90% of treatment failure. For this reason, there is an urgent need for new a...

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Detalles Bibliográficos
Autores principales: Gruber, Lisa, Abdelfatah, Sara, Fröhlich, Tony, Reiter, Christoph, Klein, Volker, Tsogoeva, Svetlana B., Efferth, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017613/
https://www.ncbi.nlm.nih.gov/pubmed/29642419
http://dx.doi.org/10.3390/molecules23040841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017613/
https://www.ncbi.nlm.nih.gov/pubmed/29642419
http://dx.doi.org/10.3390/molecules23040841

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