Molecular Modeling and Structural Stability of Wild-Type and Mutant CYP51 from Leishmania major: In Vitro and In Silico Analysis of a Laboratory Strain

Cutaneous leishmaniasis is a neglected tropical disease and a major public health in the most countries. Leishmania major is the most common cause of cutaneous leishmaniasis. In the Leishmania parasites, sterol 14α-demethylase (CYP51), which is involved in the biosynthesis of sterols, has been ident...

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Detalles Bibliográficos
Autores principales: Keighobadi, Masoud, Emami, Saeed, Lagzian, Milad, Fakhar, Mahdi, Rafiei, Alireza, Valadan, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017637/
https://www.ncbi.nlm.nih.gov/pubmed/29562710
http://dx.doi.org/10.3390/molecules23030696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017637/
https://www.ncbi.nlm.nih.gov/pubmed/29562710
http://dx.doi.org/10.3390/molecules23030696

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