Investigation of an (18)F-labelled Imidazopyridotriazine for Molecular Imaging of Cyclic Nucleotide Phosphodiesterase 2A

Specific radioligands for in vivo visualization and quantification of cyclic nucleotide phosphodiesterase 2A (PDE2A) by positron emission tomography (PET) are increasingly gaining interest in brain research. Herein we describe the synthesis, the (18)F-labelling as well as the biological evaluation o...

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Detalles Bibliográficos
Autores principales: Schröder, Susann, Wenzel, Barbara, Deuther-Conrad, Winnie, Teodoro, Rodrigo, Kranz, Mathias, Scheunemann, Matthias, Egerland, Ute, Höfgen, Norbert, Briel, Detlef, Steinbach, Jörg, Brust, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017663/
https://www.ncbi.nlm.nih.gov/pubmed/29498659
http://dx.doi.org/10.3390/molecules23030556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017663/
https://www.ncbi.nlm.nih.gov/pubmed/29498659
http://dx.doi.org/10.3390/molecules23030556

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