High Level Expression and Purification of the Clinically Active Antimicrobial Peptide P-113 in Escherichia coli

P-113, which was originally derived from the human saliva protein histatin 5, is a histidine-rich antimicrobial peptide with the sequence AKRHHGYKRKFH. P-113 is currently undergoing phase II clinical trial as a pharmaceutical agent to fight against fungal infections in HIV patients with oral candidi...

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Detalles Bibliográficos
Autores principales: Cheng, Kuang-Ting, Wu, Chih-Lung, Yip, Bak-Sau, Yu, Hui-Yuan, Cheng, Hsi-Tsung, Chih, Ya-Han, Cheng, Jya-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017664/
https://www.ncbi.nlm.nih.gov/pubmed/29601518
http://dx.doi.org/10.3390/molecules23040800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017664/
https://www.ncbi.nlm.nih.gov/pubmed/29601518
http://dx.doi.org/10.3390/molecules23040800

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