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Optimization of the Preparation Conditions of Borneol-Modified Ginkgolide Liposomes by Response Surface Methodology and Study of Their Blood Brain Barrier Permeability

Ginkgolides (GG), containing ginkgolide A (GA), ginkgolide B (GB) and ginkgolide C (GC), are mainly prescribed for ischemic stroke and cerebral infarction. However, the ginkgolides can hardly pass the blood-brain barrier (BBB) into the brain. The purpose of this study was to prepare borneol-modified...

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Detalles Bibliográficos
Autores principales: Lv, Zhiyang, Yang, Yuwei, Wang, Jie, Chen, Jing, Li, Junsong, Di, Liuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017666/
https://www.ncbi.nlm.nih.gov/pubmed/29385087
http://dx.doi.org/10.3390/molecules23020303