Halo-Substituted Chalcones and Azachalcones Inhibited Lipopolysaccharited-Stimulated Pro-Inflammatory Responses through the TLR4-Mediated Pathway

A series of B-ring, halo-substituted chalcones and azachalcones were synthesized to evaluate and compare their anti-inflammatory activity. Mouse BALB/c macrophage RAW 264.7 were pre-treated with 10 μg/mL of each compound for one hour before induction of inflammation by lipopolysaccharide (1 μg/mL) f...

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Detalles Bibliográficos
Autores principales: Shih, Tzenge-Lien, Liu, Ming-Hwa, Li, Chia-Wai, Kuo, Chia-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017711/
https://www.ncbi.nlm.nih.gov/pubmed/29518899
http://dx.doi.org/10.3390/molecules23030597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017711/
https://www.ncbi.nlm.nih.gov/pubmed/29518899
http://dx.doi.org/10.3390/molecules23030597

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